Retrovirus Gene Therapy

Long-term correction of genetic diseases requires permanent integration of therapeutic genes into chromosomes of affected cells. Gene therapy enables modification of cell by the replacement of non-functional or missing gene, suppression of another gene, or induction of cell death as in the case of oncologic diseases. Monogenic diseases and age-related disorders can be treated by retrovirus-mediated gene therapy, but (retro)viral vectors are most frequently used in cancer gene therapy. Full throttle remastered walkthrough.